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KMID : 0351619750160020017
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Kyungpook Medical Journal
1975 Volume.16 No. 2 p.17 ~ p.28
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Resistance to Antibacterial Substances and the Effect on the Administration of These Substances on Urinary Pathegens
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鄭洙光/Cheong, Soo Kwang
徐城鐸/全燾基/Suh, Sung Taik/Chun, Do Ki
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Abstract
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The resistance to antibacterial substances of urinary pathogens and the effect of the administration of antibacterial substances on the resistance and bacterial counts in urines were studied.
Stapzylococctcs, Esche~ ichia coli, dlebsiella, Enterobacter, Aikaligenes, Proteus, Serratia, and Pseudomcnas were isolated from urines of patients suffering from urinary infections. Most strains were r~sistant to chlcra ~phenicol, tetracycline, streptomycin, sulfonamide, penicillin, ampicillin (AP), kanamycin (KJI), erythromycin and carbenicillin, and sensititi-e to gentamicin (GM), but all strains of Pseudcmonas were resistant to these susbstances including GM. The administration of doxycycline, a derivate of tetracyclines, AP and KM resulted in the disappearance or diminution of Klebsiella, Enterobacter and Alkaligenes in urines, but the bacterial counts of Pseudomonas in urines were not influenced by the use of these drugs and even by GM. Strains of first isolation rom the same patients were resistant to the antibacterial substances, and the use cf these substantes did not result in the marked increase in the resistance of causative agents.
The secondary infections of E. coli and Pseudomonas were noted, and these :ere considered to 1~ nosocoi~ial infections. The strains were also highly resistant to antibac~e: i1 substances used, and the prevention of secondary hospital infection was emphasized.
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KEYWORD
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